Endocrine Pathology

For each of the following patients, select the most likely pathologic finding:

1. A 42-year-old man has recently passed a urinary calculus that is composed of calcium oxalate. He has abdominal pain, and upper GI endoscopy reveals several sharply demarcated 1 cm gastric antral ulcerations. He has pain in his lower extremities:

2. A 51-year-old woman has increasing lethargy and darker skin tone for 6 months. On examination she is hypotensive. Laboratory studies show Hgb 12 g/dL, sodium 132 mmol/L, potassium 3.4 mmol/L, chloride 100 mmol/L, HCO3- 21 mmol/L, glucose 65 mg/dL, and creatinine 1 mg/dL:

3. A 20-year-old woman has exhibited increased nervousness for several months. She has palpitations. She has lost 7 kg without dieting or a change in exercise patterns:

4. A 39-year-old man has a blood pressure of 160/100 mm Hg that persists for months. A serum chemistry panel shows sodium 141 mmol/L, potassium 2.8 mmol/L, chloride 101 mmol/L, CO2 25 mmol/L, glucose 90 mg/dL, creatinine 1.2 mg/dL, and urea nitrogen 15 mg/dL:

5. A 42-year-old woman is found to have a palpable neck mass on routine physical examination. Imaging procedures show a 'cold' nodule in the thyroid along with an enlarged lymph node:

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A. Addison disease B. Conn syndrome C. Craniopharyngioma D. Cretinism E. Cushing syndrome
F. DeQuervain disease G. DiGeorge syndrome H. Follicular adenoma I. Graves disease J. Iodine deficiency
K. Medullary carcinoma L. MEN I M. MEN IIa N. Pancreatic neuroendocrine tumor O. Papillary carcinoma
P. Parathyroid carcinoma Q. Parathyroid hyperplasia R. Pheochromocytoma S. Prolactinoma T. Sheehan syndrome


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