Breast Pathology

For each of the following patients, select the most likely pathologic finding:

1. A 33-year-old woman has noted a bloody nipple discharge from her right breast for the past month, but there is no pain or swelling, and no masses are palpable. There is no axillary lymphadenopathy:

2. A 23-year-old woman has discovered the presence of a firm rubbery movable nodule in upper outer quadrant of her left breast while doing a self-examination. She notes that the nodule appears slightly larger and more tender during menstrual periods, but the mass has seemed to remain about the same size for the past 4 months. She has no axillary lymphadenopathy:

3. A 15-year-old adolescent male has noticed that he has had an increased size to his left breast which has occurred gradually over the past year. There is no pain or tenderness. No mass is palpable:

4. A 45-year-old woman has some ill-defined lumpiness in her left breast, and a mammogram reveals some irregular areas of increased density. Following a needle biopsy, a mastectomy and axillary node dissection are performed, with lymph nodes negative. Then a similar lesion is found in the opposite breast a year later:

5. A 21-year-old woman develops amenorrhea and galactorrhea that persists for several months, even though she has never been pregnant. There are no breast masses and no pain or tenderness:

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A. Abscess B. Amastia C. Atypical epithelial hyperplasia D. Colloid carcinoma E. Ductal carcinoma in situ
F. Fat necrosis G. Fibroadenoma H. Gynecomastia I. Intraductal papilloma J. Implant, silicone, leaking
K. Infiltrating ductal carcinoma L. Lobular carcinoma in situ M. Medullary carcinoma N. Metastatic carcinoma O. Metaplastic carcinoma
P. Paget disease Q. Pregnancy R. Prolactinoma S. Phyllodes tumor T. Sclerosing adenosis


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