Normal Structures
| Structure | Description
|
|---|
| Neutrophil | Normal polymorphonuclear leukocyte
| | Lymphocyte | Normal lymphocyte
| | Plasma cell | Normal plasma cell with prominent cytoplasmic smooth endoplasmic reticulum
| | Macrophage | Normal macrophage with oblong nucleus, nucleolus, and cytoplasm with a variety of inclusions
| | Platelets | Normal platelets
| | Mitochondria | Happy mitochondria within a cell
| | Skeletal muscle | Normal skeletal muscle, normal (inset shows a single sarcomere with dark Z discs, and a central M line, with thin actin and thick myosin filaments)
| | Collagen | Normal collagen fibrils
| | Cilia | Normal cilia of respiratory tract epithelium
|
Miscellaneous Findings
| Structure | Description
|
|---|
| Amyloid | Amyloid fibrils, with inset demonstrating array of fibrils
| | Adrenoleukodystrophy | Adrenoleukodystrophy, adrenal gland, with long parallel inclusions of long chain fatty acids
| | Birbeck granules | Birbeck granules (inset shows several at higher magnification) from a case of histiocytosis X
| | Histiocytosis X | Cell with a clefted nucleus from a case of histiocytosis X
| | Bacteria | Pseudomonas bacteria
| | Cryptosporidia | Cryptosporidia along small intestinal brush border
| | Herpes simplex virus | Herpes simplex virus in brain, viral particles (inset) in nucleus
| | JC papovavirus | Progressive multifocal leukoencephalopathy (PML) with JC virus in brain, small round dark viral particles in nucleus
| | HIV-1 | Human immunodeficiency virus, viral particles at low magnification adjacent to cell surface
| | HIV-1 | Human immunodeficiency virus, viral particles at medium magnification
| | HIV-1 | Human immunodeficiency virus, viral particle budding from cell surface at top, and complete viral particle at bottom, high magnification
| | Inclusion body myositis | Skeletal muscle with inclusion body myositis
| | Nemaline myopathy | Skeletal muscle with nemaline rods
| | Ciliary dyskinesis | Respiratory tract cilia lacking dynein arms
|
Neoplasms
| Structure | Description
|
|---|
| Adenocarcinoma | Adenocarcinoma with several features typical of a neoplasm of epithelial origin, including a junctional complex (tight junction at asterisk, desmonsomes at crosses, and a mucin granule M) and lumenal microvilli at the upper right
| | Junctional complex | Junctional complex, higher magnification, with tight junction at right and desmosomes at left
| | Squamous cell carcinoma | Squamous cell carcinoma with many desomosomes and cytoplasmic tonofilaments streaming to the left
| | Microvilli | Microvilli seen in cell from adenocarcinoma of the colon (inset shows the dense core rootlets below and the rounded glycocalyceal bodies in the villi above
| | Intracytoplasmic lumen | Intracytoplasmic lumen in a cell from metastatic carcinoma of breast
| | Leiomyosarcoma | Leiomyosarcoma demonstrating cytoplasmic filaments with condensations to the left of the nucleus, a lipid body at the far left, and subplasmalemmal filament condensations and pinocytotic vesicles near nucleus at the right (also seen in the inset)
| | Mesothelioma | Mesothelioma of pleura with long, curved microvilli
| | Ewing's sarcoma | Ewing's sarcoma of bone with extensive cytoplasmic glycogen deposits
| | Premelanosomes | Premelanosomes from a malignant melanoma, composite of two cases
| | Melanosomes | Melanosomes (inset shows the dark oblong melanosomes in more detail) from a malignant melanoma
| | Adrenal carcinoma | Large mitochondria with tubular cristae above normal mitochondria in a cell from adrenal cortical carcinoma
| | Neurosecretory granules | Neurosecretory granules (some with a thin surrounding halo) in a neuroendocrine neoplasm
|
Renal Lesions
|
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