Question 6

A 61-year-old woman comes to her physician because of a change in the appearance of her right breast over the past 7 months. On physical examination the skin overlying the breast is indurated, roughened, and reddish-orange. There is nipple retraction. The gross appearance of the cut surface of her subsequent mastectomy specimen is shown here. Which of the following is the most likely diagnosis?

A)    Infiltrating ductal carcinoma
B)    Intraductal carcinoma
C)    Phyllodes tumor
D)    Lobular carcinoma in situ
E)    Sclerosing adenosis