The cerebral atrophy seen here mainly in the frontal and parietal regions is characterized by narrowed gyri along with widened sulci. The atrophy seen here was due to dementia of the Alzheimer type (Alzheimer disease) marked by progressive loss of higher mental function.

Which of the following cell types is primarily lost with Alzheimer disease?

A Astrocyte

B Ependymal cell

C Microglial cell

D Neuron

E Oligodendrocyte